Wednesday, August 18, 2010

Funny calculations

Swarupmay Majumdar what does 2% of xylazine means? 1 ml contains 2 mg or 20mg?..can any vet help me???

about an hour ago · ·
    • Sushil Kumar Paudel ‎20mg/ml
      about an hour ago · · 1 person ·
    • Nassem N. Naimi what about 10% metronidazole? how many mg/ml
      about an hour ago · ·
    • Amit Bhardwaj is it weight by volume or volume by volume???????
      about an hour ago · ·
    • Bhushan Chaudhari each ml contains 23.32mg
      about an hour ago · ·
    • Swarupmay Majumdar good question..Naseem only can say
      about an hour ago · ·
    • Nassem N. Naimi I dont know That is what is written there Only 10% :D
      Metro dose is 15mg/kg!!
      about an hour ago · ·
    • Bhushan Chaudhari ‎@nassem: 5 mg/ml
      about an hour ago · ·
    • Swarupmay Majumdar how???
      about an hour ago · ·
    • Nassem N. Naimi ‎2% -> 20 mg/ml
      10%-> 5mg/ml :D whattttttttt???
      about an hour ago · ·
    • Sushil Kumar Paudel If i am not wrong::::: mostly we see W/V for that::::::Volume percent =
      weight of solute (in g)
      volume of solution (in mL)

      x 100
      about an hour ago · ·
    • Swarupmay Majumdar thats the calculation naseem
      about an hour ago · ·
    • Sushil Kumar Paudel ‎10% metro means:::::: 100mg/ml
      about an hour ago · ·
    • Sushil Kumar Paudel just one more "0" hahahahahahahaha
      about an hour ago · ·
    • Amit Bhardwaj ‎2% xylazine means that the active ingredient i.e. xylazine is 2 units in the total 100 unit solutions
      or the right dose will be 20mg/ml, calculate as per the dose rate and administer
      about an hour ago · ·
    • Nassem N. Naimi man in human they give human 100ml of 10% metronidazole
      about an hour ago · ·
    • Nassem N. Naimi I give 6 ml/ kg metro 10% and no sign of toxicity (for 5 days)
      about an hour ago · ·
    • Nassem N. Naimi ‎600mg/kg should be toxic for usre!!
      about an hour ago · ·
    • Amit Bhardwaj what is the dose rate of metronidazole and what is the strength of the drug (on the vial), now the total drug to be administered will depend on both the factors
      about an hour ago · ·
    • Satya Pal ‎2%xylazine means 2 grm in 100ml which can be written as 2000 mg in 100ml so 1ml contains 20 mg...
      about an hour ago · · 1 person ·
    • Swarupmay Majumdar my god! who is this
      about an hour ago · ·
    • Nassem N. Naimi the dose is 15-20 mg /kg :)
      on the vial it is written 10% metronidazole
      so if in each ml there is 100mg so I am giving 600mg/kg which is around 30 times the normal dose :P so the animal would be DEAD!!!
      about an hour ago · ·
    • Swarupmay Majumdar where will u get 100 ml xylazine? but it nice to understand the calculation
      about an hour ago · ·
    • Satya Pal sr is it wrong??????/pls correct me..
      about an hour ago · ·
    • Swarupmay Majumdar naseem , the whole bottle of metronidazole contains only 100mg metronidazole not anything more
      about an hour ago · ·
    • Swarupmay Majumdar ‎@sp: U made it easy. Thats correct
      about an hour ago · ·
    • Nassem N. Naimi ‎100mg in 100ml :)
      so 10% --> 1 mg ??? so I have to give 15 - 20 ml/ kg? so 2 bottles for 20kg dog???

      Doesnt make since to me :P
      about an hour ago · ·
    • Swarupmay Majumdar yes
      about an hour ago · ·
    • Swarupmay Majumdar
      Signs of intoxication associated with metronidazole in dogs and
      cats, include anorexia and/or vomiting, depression, mydriasis, nystagmus, ataxia, head-tilt, deficits of
      proprioception, joint knuckling, disorientation, tremors, seizures, brady...See More
      about an hour ago · ·
    • Swarupmay Majumdar
      Doses -
      Dogs:
      For treatment of Giardia:
      a) 44 mg/kg PO initially, then 22 mg/kg PO q8h for 5 days. (Todd, Paul, and DiPietro
      1985)
      ...See More
      about an hour ago · · 1 person ·
    • Swarupmay Majumdar Metronidazole 500 mg/100 ml injection (ready to use); Flagyl¨I.V. (Searle); Metro¨I.V.
      about an hour ago · ·
    • Sushil Kumar Paudel its so easy my frens,,,, one more "0" yar,,,, no need to pay for that "0",,, LOL!!!!!!!!!!!!!!!!!!!!
      about an hour ago · · 1 person ·
    • Nassem N. Naimi so now my new question is
      If metronidazole 10% is 100mg/ml and I am giving around 2 to 5 ml /kg
      so I am giving 200 to 500 mg/kg
      and the dose is 15 up to 50 mg /kg why no animal showed any signs of toxicity after all that??
      about an hour ago · ·
    • Swarupmay Majumdar ‎10% metronidazole means 10gm in 100ml
      about an hour ago · ·
    • Swarupmay Majumdar ask the metronidazole botle..does it really contain metronidazole
      about an hour ago · ·
    • Sushil Kumar Paudel ‎@Dr. Nassem,,,,, i am wondering is that 10% metronidzole information labelled is true?????????
      about an hour ago · ·
    • Swarupmay Majumdar hahah...naseem
      about an hour ago · ·
    • Sushil Kumar Paudel i may be wrong!!!! but i am really wondering!!!!
      about an hour ago · ·
    • Nassem N. Naimi I get human Metronidazole I got it from Hospital and this is not the 1st brand before I used another 10% brand (50ml too) and as I said no toxicity been seen
      sorry the 1st bottle is 50ml too!!!
      about an hour ago · ·
    • Rajshankar Tony Sarma
      K. 1% is always 10mg/ml.

      So:
      2% (xylazine) = 20mg/ml
      2.5% (enrofloxacin) = 25mg/ml
      ...See More
      about an hour ago · · 1 person ·
    • Vikram Dave ‎2% xylazine is 20mg/ml while 10% metro is 5 mg/ml
      about an hour ago · · 1 person ·
    • Rajshankar Tony Sarma Vikram - the percentage works out how many mg of active ingredient there are per ml (well, in theory, how many kilogrammes per litre!). So, by definition, 10% MUST be 100mg/ml (as for ketamine). 5mg/ml is 0.5%.
      about an hour ago · ·
    • Sushil Kumar Paudel i think that might be 0.1% metronidazole preparation!!!
      58 minutes ago · ·
    • Nassem N. Naimi Man We need some pharmacologist :P hehehe
      Our teacher was not a good one :P
      55 minutes ago · · 1 person ·
    • Jayant Yadav Each ml solution contains:
      20 mg xylazine....dr jayant yadav..vet...099990-39993
      53 minutes ago · ·
    • Dinesh Dwivedi ‎20 mg,100ml contains 2000mg(2%)
      53 minutes ago · ·
    • Jayant Yadav Dogs : iv or im 0.15 ml/kg b.w.....
      51 minutes ago · ·
    • Avinash Shedge ‎2 % technically means 2 parts in 100 parts.. 2gm in 100 ml( gms )
      50 minutes ago · ·
    • Avinash Shedge i.e. 2000mg in 100 ml .. i.e. 20 mg in 1 ml ..
      49 minutes ago · · 1 person ·
    • DrMehul Joshi ‎20 mg in 1 ml
      48 minutes ago · ·
    • Rajshankar Tony Sarma
      I guess that part of the problem is that on bottles they sometimes quote the precise number of milligrammes of e.g. active ingredient X "as the hydrochloride". What actually matters is the effective amount of active ingredient per ml, which...See More
      48 minutes ago · ·
    • Arvinda Panthee ‎20 mg/ml
      44 minutes ago · ·
    • Rajshankar Tony Sarma We are all clearly clinicians rather than mathematicians! :oD

      Still, I've never seen a mathematician save a cute puppy...
      41 minutes ago · · 1 person ·
    • Swarupmay Majumdar Naseem this last note is ur take home point!!!
      40 minutes ago · ·
    • 向恆逸 Dr.Majumdar, 2% Xylazine should mean 20mg/mL.
      I think this infromation have be shown on the label of the vail.
      31 minutes ago · ·
    • Zain Khalid its here 1ml contains 20mg....
      30 minutes ago · ·
    • Praveen Raja Kosuri its 20mg in 1ml
      24 minutes ago · ·
    • DrKumar Ravi ‎1 ml contains 23 mg approx but when use clinically we take it as 1ml contains 20mg
      17 minutes ago · ·
    • Rajshankar Tony Sarma Ravi - see above - it's all about the formulation, xylazine "as hydrochloride"!
      15 minutes ago · ·

No comments:

Post a Comment

If you are willing to see the full discussion on this topic happening on Facebook, click this link and join in SAVIN forum for Vets In small Animal Practice "http://www.facebook.com/group.php?gid=205150136887"